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From: [email protected]
Date: 24/04/05
Time: 04:12:49
Remote Name: 218.77.47.93
Camptothecine Camptothecin 10-Hydroxy camptotheccnum 9-Nitrocellulose camptotheccnum Camptothecine Camptothecin 10-Hydroxy camptotheccnum 9-Nitrocellulose camptotheccnum PHYSICAL PROPERTIES RAW MATERIAL Nothapodytes foetida (wt) miers (Icainaceae) PREPARATION Total extractives of Powdered wood suing a solvent, further processing and purification. PHYSICAL CHARACTERISTICS Pale yellow coloured powder, mp 257-260 deg. C soluble in DMF (Dimethyl formamide) CHEMICAL CHARACTERISTICS COMMON NAMES Camptothecine CHEMICAL NAME (S) 4-Ethyl-4-hydroxy-IH-Pyrano(3กฏ4กฏ6กฏ7) indolizino (1,2,-b) quinoline 3,14 (4H, 12H)-dione MOLECULAR FORMULA C20 H16 N2 04 MOLECULAR WEIGHT 346.34 IDENTIFICATION IR (KBr) UV (Max) Specific Optical rotation V max 3400 1745 1655 1605 & 1580 cm l max 220, 253 & 358 nm +31.3 deg. (in Chloroform-methanol) PURITY USP Std By HPLC 98% +. TOXICITY Highly Toxic USE Anti Cancer activity, Raw material for Topotecan, CPT-11.