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From: [email protected]
Date: 24/08/05
Time: 04:30:09
Remote Name: 220.168.15.132
Dear Manager, How are you and thanks very much for all of your support during the past years! Re: Sesamin Extract We have the best quality Sesamin Extract in stock for sale, we will offer our long term business partners the lowest price in the world for this product. Product Information of Bio-samin Bio-samin: Black Sesame Extracted Sesamin Basic Info Formal Name: [1S-(1α,3aα,4α,6aα)]-5,5’-(tetrahydro-1H,3H furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole Molecular Formula C20H18O6 Molecular Weight 354.4 Odor : Characteristic Purity: No Less Than 90% Stability: ≥ 3 years at -20°C Supplied as: A crystalline solid UV/Vis: λmax: 235, 286 nm Laboratory Procedure For long term storage, we suggest that sesamin be stored as supplied at -20°C. It will be stable for at least three years. Sesamin is supplied as a crystalline solid. A stock solution may be made by dissolving the sesamin in an organic solvent purged with an inert gas. Sesamin is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of sesamin in these solvents is 0.5, 12, and 33 mg/ml, respectively. Sesamin will be stable for at least six months in these solvents if stored at -20°C. Sesamin is sparingly soluble in aqueous buffers. Further dilutions of the stock solution into aqueous buffers or isotonic saline should be made prior to performing biological experiments. For maximum solubility in aqueous buffers, sesamin should first be dissolved in DMF and then diluted with the aqueous buffer of choice. Sesamin has a solubility of 50 µg/ml in a 1:10 solution of DMF:PBS (pH 7.2) using this method. Store aqueous solutions of sesamin on ice and use within 12 hours of preparation. Although the aqueous solutions of sesamin may be stable for more than 12 hours, we strongly recommend using a fresh preparation each day. Sesamin is a non-competitive inhibitor of ∆5-desaturase. It inhibits the conversion of dihomo-γ-linolenic acid to arachidonic acid with a Ki value of 155 µM in rat liver microsomes.1 Reference 1. Shimizu, S., Akimoto, K., Sugano, M., et al. Studies on desaturase inhibitors of polyunsaturated fatty acid biosynthesis, in Essential Fatty Acids and Eicosanoids. Sinclair, A. and Gibson, R., editors. American Oil Chemist Society, Champaign, 37-41 (1992). Wish you all of the best and regards! If there are any further questions, please don't hesitate to contact us. Sincerely yours, Frank Liu Manager Organic Herb Inc. Phone: +86 731 4060828 Mobile: +86 135 07462863 Fax +86 731 4023669 E-Mail: [email protected] Website: http://www.organic-herb.com -----------------------Natural Way to Better Life!